منابع مشابه
Review of Salivary Gland Neoplasms
Salivary gland tumours most often present as painless enlarging masses. Most are located in the parotid glands and most are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but most cases will require surgical excision as a...
متن کاملTP53 mutations in salivary gland neoplasms.
Many studies have demonstrated that loss of TP53 gene function has an important role in the genesis of many neoplasms, including salivary gland neoplasms. The purpose of this study was to examine the mutation profile of the TP53 gene in salivary gland neoplasms. Genomic DNA was extracted from paraffin-embedded tissues of pleomorphic adenoma, carcinoma in pleomorphic adenoma, mucoepidermoid carc...
متن کاملA Review of Signet Ring cells in Salivary Gland Tumors
Objectives: Signet Ring Cells (SRCs) are often seen in gastrointestinal, breast, bile duct and lung invasive carcinomas. Observing these cells in benign and malignant lesions of the salivary glands is not common. Signet-ring cell adenocarcinoma is rare and is commonly seen in the secondary salivary glands. Although, the presence of SRCs in other neoplasms of the body is usually associated with ...
متن کامل[Epidemiologic profile of salivary gland neoplasms: analysis of 245 cases].
AIM The aim of the present study is to establish the relative frequency and distribution of benign and malignant epithelial neoplasms of salivary glands in the Pathology and Cytology Laboratory, STUDY DESIGN Historic cohort. MATERIAL AND METHOD in the state of Sergipe, during the period 1980-1999. The neoplasms were individualized by gender, age, race of the patients, anatomic localization ...
متن کاملImmunolocalization of DNMT1 and DNMT3a in salivary gland neoplasms.
OBJECTIVE Salivary gland neoplasms pathogenesis has not been well established. DNA methylation occurs when methyl groups are added to cytosine nucleotides in specific areas of the gene by the enzyme DNA methyltransferase (DNMT). This chemical modification can alter gene expression without altering DNA sequence. While DNMT3a is mostly involved in de novo methylation, DNMT1 acts as a maintenance ...
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ژورنال
عنوان ژورنال: ISRN Otolaryngology
سال: 2012
ISSN: 2090-5750
DOI: 10.5402/2012/872982